Tennessee Retina is an active participant in many national research trials. The efforts of our physicians and patients have led to the approval of many treatments now considered to be the standard of care, and our continuing involvement in clinical research offers access to new and potentially superior treatments to patients with sight-threatening conditions.
Please call 615-983-6000 for more information and participation criteria in our active clinical trials.
Active Clinical trials
AMD
Neovista CABERNET Study (CNV Secondary to AMD Treated with BEta RadiatioN Epiretinal Therapy) - compares epiretinal beta radiation therapy to the standard treatment with Lucentis injections. www.neovistainc.com
NIH CATT Study (Comparison of Age-related Macular Degeneration Treatment Trials) - compares the safety and effectiveness of Lucentis versus Avastin injections. www.med.upenn.edu/cpob/studies/CATT.shtml
Genentech DO-DO Study – compares dosing intervals using standard dose and DOuble DOses of Lucentis injections
Regeneron View 1 Study – compares the effectiveness of the drug VEGF-Trap versus the standard drug Lucentis
Sirion Fenretinide Study- controlled dose study of orally administered fenretinide in the treatment of geographic atrophy in subjects with dry AMD. This study has a 2 year commitment with 9 total visits (enrollment is closed).
Retinal Vein Occlusion
Genentech Bravo Study - test the safety and effectiveness of a new drug delivery system and steroid for the treatment of macular edema due to branch retinal vein occlusion
Genentech Cruise Study - test the safety and effectiveness of a new drug delivery system and steroid for the treatment of macular edema due to central retinal vein occlusion
Diabetic Retinopathy
Genentech Rise Study - test the safety and effectiveness of Lucentis injections for the treatment of diabetic macular edema
PAST CLINICAL TRIALS
PTAMD Study (Iridex) - A multi-center, randomized study designed to assess the effectiveness of diode laser treatment in patients with non-exudative AMD in comparison with the natural progression of the disease.
Vitrase for Vitreous Hemorrhage Study (Advanced Corneal Systems) - investigated the safety and effectiveness of intravitreal injections of Vitrase for vitreous hemorrhage
TTT4CNV Trial (Iridex)- A multi-center, randomized study designed to assess the effectiveness of transpupillary thermotherapy in patients with occult subfoveal choroidal neovascularization due to AMD.
VAM Study (Cibavision)- A multi-center safety study of the treatment of predominantly classic subfoveal CNV secondary to AMD using photodynamic therapy with vertoporfin for injection.
TSV25 Clinical Trial (Bausch & Lomb, Inc)- A multi-center, prospective study to evaluate the safety and sutureless capability of the TSV25 vitrectomy system.
Ex PS DDS in the treatment of persistent macular edema (Oculex Pharmaceuticals)- A phase 2 randomized, multi-center, controlled trial to assess the safety and effectiveness of dexamethasone posterior segment drug delivery system (DEX PS DDS) in the treatment of persistent macular edema.
ANCHOR (Genentech)- A phase III, multi-center, randomized, double-masked, active treatment-controlled study of the efficacy and safety of Ranibizumab compared with verteporfin photodynamic therapy in subjects with predominantly classic subfoveal neovascular age-related macular degeneration.
MARINA (Genentech)- A phase III, multi-center, randomized, double-masked, sham injection-controlled study of the efficacy and safety of rhuFab V2 in subjects with minimally classic or occult subfoveal neovascular age-related macular degeneration.
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Our study patients are very important to us and we provide them with exceptional care and attention. Please contact your current eyecare provider to see if you may qualify for one of our studies, or contact one of our Clinical Trial staff members listed below with any questions @ 615-983-6000
Mary Ann McCain, RN, CNOR - Clinical Research Manager
Kelly Winters, COA - Clinical Research Coordinator
Sarah Hines, COA - Clinical Research Coordinator
Rachel Beck - Clinical Research Assistant
