Persistent Fetal Vasculature
Persistent Fetal Vasculature (PFV) is a rare congenital eye condition that occurs when blood vessels that normally support the developing eye before birth do not fully disappear as they should. These remaining blood vessels and associated tissues can affect the normal development and structure of the eye, potentially impacting vision.
PFV is typically present at birth or becomes noticeable shortly afterward. It most often affects one eye, although both eyes can be involved. The condition can vary significantly in severity, and its effects depend on which structures of the developing eye are affected.
Children with PFV may have:
- Crossed or misaligned eyes (strabismus)
- Abnormal eye movements (nystagmus)
- Reduced vision or amblyopia ("lazy eye")
- An eye that appears smaller than the other
- A white or unusual appearance in the pupil
PFV is generally not a progressive disease itself. However, as the eye grows, abnormal tissues can place traction on structures within the eye and contribute to changes that may affect vision.
Treatment is individualized based on the severity of PFV and how it is affecting the eye and vision. In some cases, observation may be appropriate, while other children may benefit from treatment to address structural abnormalities or related vision problems.
