Understanding Ocular Lymphoma

Did you know lymphoma can affect the eye?
September is Lymphoma Awareness Month, a time to increase awareness of lymphoma and the different ways this disease can affect the body. While lymphoma is commonly associated with the lymphatic system, it can also affect the eyes.
Ocular lymphoma refers to lymphoma that involves structures of the eye or the tissues surrounding it. It is a rare condition that can take different forms, depending on the area affected.
What Is Ocular Lymphoma?
Ocular lymphoma is a type of cancer involving lymphocytes, a kind of white blood cell. It may affect different parts of the eye, including the tissues around the eye, the surface of the eye, or structures within the eye.
One form is primary vitreoretinal lymphoma (PVRL), which affects the vitreous and retina. PVRL is closely associated with primary central nervous system lymphoma, a related disease that affects the brain and spinal cord.
Because ocular lymphoma can involve different parts of the eye and may resemble other eye conditions, recognizing the possibility of this rare disease is an important part of specialized eye care.
Recognizing the Importance of Eye Health
Changes in vision can have many different causes. Depending on the type and location of ocular lymphoma, patients may experience changes in vision or other eye-related symptoms. However, these symptoms are not specific to lymphoma and can also occur with more common eye conditions.
Persistent or unexplained changes in vision should be evaluated by an eye care professional. A thorough examination can help determine whether additional testing or evaluation is needed.
How Is Ocular Lymphoma Evaluated?
Evaluating a suspected ocular lymphoma may involve a detailed eye examination, specialized imaging, and other diagnostic testing. The approach depends on the suspected type of lymphoma and the structures involved.
In some cases, additional testing or a tissue or fluid sample may be necessary to help establish a diagnosis. Because ocular lymphoma can be complex and may be associated with lymphoma elsewhere in the body, evaluation beyond the eye may also be part of a patient's care.
Specialized Ocular Oncology Care
Tennessee Retina has a dedicated Ocular Oncology team with extensive experience evaluating and managing rare and complex eye conditions, including ocular lymphoma. Our team works closely with patients and their care teams to develop an individualized treatment plan based on each diagnosis.
Led by Dr. David Reichstein, vitreoretinal surgeon and ocular oncologist, our team provides specialized expertise for patients with complex eye tumors and other ocular cancers.
If you experience persistent or unexplained changes in vision, speak with an eye care professional about an appropriate evaluation.


